PMH48 COST-EFFECTIVENESS OF QUETIAPINE EXTENDED RELEASE VERSUS PAROXETINE AND LITHIUM IN ACUTE BIPOLAR DEPRESSION
نویسندگان
چکیده
منابع مشابه
Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression.
Background: To evaluate the effectiveness of quetiapine extended release once daily in bipolar depression. Methods: Double-blind, placebo-controlled study in acutely depressed adults with bipolar I or II disorder, with or without rapid cycling.Patients were randomized to 8 weeks of quetiapine extended release(XR) 300 mg daily monotherapy or placebo.The primary out come measure was changed from ...
متن کاملCost effectiveness of quetiapine in patients with acute bipolar depression and in maintenance treatment after an acute depressive episode.
BACKGROUND Bipolar disorder has a significant impact upon a patient's quality of life, imposing a considerable economic burden on the individual, family members and society as a whole. Several medications are indicated for the acute treatment of mania and depression associated with bipolar disorder as well as for maintenance therapy; however, these have varying efficacy, tolerability and costs....
متن کاملThe cost-effectiveness of mirtazapine versus paroxetine in treating people with depression in primary care.
Currently, there are no data available comparing cost-effectiveness of two antidepressants in the primary care setting in the UK. Alongside a randomized, double-blind, 24-week study of mirtazapine and paroxetine, data were prospectively collected on patients' use of hospital and non-hospital services and days off work. Costs were estimated in each treatment arm from National Health Service (NHS...
متن کاملQuetiapine monotherapy for bipolar depression
Bipolar depression is more common, disabling, and difficult-to-treat than the manic and hypomanic phases that define bipolar disorder. Unlike the treatment of so-called "unipolar" depressions, antidepressants generally are not indicated as monotherapies for bipolar depressions and recent studies suggest that -even when used in combination with traditional mood stabilizers - antidepressants may ...
متن کاملRhabdomyolysis following Acute Extended-Release Quetiapine Poisoning: A Case Report
Background. During the past few years, there have been a number of case reports concerning rhabdomyolysis following quetiapine poisoning; however, there has been none concerning the medication in its extended-release form. Methods. We present the case report of a 48-year-old man presenting a major depressive disorder and borderline personality disorder, who after voluntary intoxication with 120...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2009
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(10)74767-7